Buy Metronidazole No Prescription

Generic Name: Metronidazole

Common Brand Name: Flagyl

Buying Metronidazole (Flagyl) Without Prescription

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• Delivery time US: typically 10 business days.
• No prescription required.

The following product information is not intended to replace the physician's or manufacturer's instructions.

Metronidazole common medical uses:
Metronidazole is an imidazole prescription antibiotic that is used in the treatment of serious infections caused by susceptible anaerobic bacteria; prophylaxis of postoperative infection in patients undergoing colorectal surgery; treatment of amebiasis; treatment of trichomoniasis and asymptomatic partners of infected patients; bacterial vaginosis.
Topical metronidazole is indicated for the treatment of rosacea.

Contraindications:

• Hypersensitivity to nitroimidazole derivatives or any component of the products.
• First trimester of pregnancy in patients with trichomoniasis.

Metronidazole dosage:

• Acute amebic dysentery and amebic liver abscess
  Adults Flagyl 375 capsules : 750 mg 3 time daily for 5 to 10 days.
• Acute amebic dysentery
  Adults Flagyl 250 mg tablets: 750 mg 3 times daily for 5 to 10 days.
• Amebic liver abscess
  Adults Flagyl 250 mg tablets: 500 or 750 mg 3 times daily for 5 to 10 days.
• Amebiasis
  Children: Flagyl 375 , Flagyl 250 mg tablets: 35 to 50 mg/kg per 24 h divided into 3 daily doses for 10 days.
• Anaerobic Bacterial Infections
  Give IV initially when treating most serious anaerobic infections.
  Adults: Usual dosage is 7.5 mg/kg (approximately 500 mg for a 70 kg adult) every 6 h (max, 4 g per 24 h) for 7 to 10 days; however, infections of the bone, joint, lower respiratory tract, and endocardium may require longer treatment.
• Bacterial Vaginosis
  Adults: 750 mg ( Flagyl ER ) daily for 7 consecutive days. Vaginal 1 applicator-full (approximately 37.5 mg metronidazole) intravaginally once or twice daily for 5days; for daily dosing, administer at bedtime
• Inflammatory Papules and Pustules of Rosacea
  Adults: Topical: Apply thin layer once daily (1% cream) or twice daily to entire affected areas after washing. Use morning and evening or as directed by health care provider. Avoid application close to eyes.
• Trichomoniasis
  Adults:
  Flagyl 375 capsules: Women: 375 mg twice daily for 7 consecutive days. When a repeat course is required, a lapse of 4 to 6 wk between courses is recommended. Flagyl 250 mg tablets: 250 mg 3 times daily for 7 consecutive days.
  One-day treatment 2 g as a single dose or in 2 divided doses of 1 g each given on the same day.
  Children: 5 mg/kg/dose 3 times daily for 7 days.

Metronidazole side effects:

• CNS: headach; dizziness; seizures; peripheral neuropathy; dizziness; vertigo; incoordination; ataxia; confusion; depression; insomnia; syncope; irritability; weakness.
• Dermatologic: thrombophlebitis; urticaria; erythematous rash; flushing.
• EENT: metallic taste; glossitis; stomatitis.
• GI: nausea; anorexia; vomiting; diarrhea; constipation; epigastric distress; cramps; pseudomembranous colitis; furry tongue; glossitis; stomatitis.
• Genitourinary: Darkening of urine; dysuria; cystitis; sense of pelvic pressure; polyuria; incontinence; vaginal Candida proliferation; decreased libido; proctitis

Metronidazole precautions:

• Children: Safety and efficacy not established, except for amebiasis.
• Elderly: Monitoring serum levels may be necessary for proper dosing.
• Liver function: Patients with severe hepatic disease metabolize drug slowly; use caution and lower dose.
• Candidiasis: Known or previously unrecognized candidiasis may present more prominent symptoms during therapy.
• Hematologic effects: Use with caution in patients with a history of blood dyscrasia.
• Neurologic effects: Seizures and peripheral neuropathy have occurred. Use extra caution with prolonged use, high doses, or history of CNS disease.

Metronidazole drug interactions

Food reduces Metronidazole absorption rate therefore it should be taken one hour before or two hours after a meal.

• Alcohol: Metronidazole taken in combination with alcohol may produce abdominal cramps, nausea, vomiting, headaches and flushing.
• Disulfiram: In a clinical trial of combined therapy with disulfiram and metronidazole in the treatment of chronic alcoholics, severe acute psychotic reactions occurred in 6 out of 29 patients.
• Warfarin: Metronidazole inhibits the breakdown of the more potent S-isomer of warfarin. This is the pharmacologically active metabolite of the racemic parent molecule. Therefore, the activity of warfarin is enhanced by metronidazole.
• Phenobarbitone: Decreases the effect of metronidazole probably due to increased metabolism.
• Cyclophosphamide and BCNU (Carmustine): Metronidazole should be used with caution in patients who are receiving BCNU or cyclophosphamide as a drug interaction shown in mice, leads to increased toxicity.

Interference with Clinical Laboratory and Other Tests:

• Metronidazole may show negative interference with continuous flow spectrophotometry of aspartate aminotransferase (previously GOT) so that hepato-cellular damage which is detectable by raised serum AST may be missed.

Pregnancy & Lactation:
Pregnancy Risk Factor: B
Although metronidazoleSome Trade Names FLAGYL Click for Drug Monograph is in the FDA category B (meaning the drug is unlikely to be harmful to the fetus), metronidazole should be avoided during the 1st trimester of pregnancy because of concerns about its mutagenicity.

Breast-Feeding:
Because of the potential for tumorigenicity, shown for metronidazole in mouse and rat studies, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Metronidazole is secreted in human milk in concentrations similar to those found in plasma.

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References:

• 1. U.S. Food and Drug Administration. Metronidazole (Flagyl) U.S. Prescribing Information. Available at (PDF format): Prescribing Information