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Buy Bupropion No Prescription
Generic Name: Bupropion hydrochloride
Common Brand Names Wellbutrin, Wellbutrin
SR, Wellbutrin XL
The following product information is not intended to replace the physician's
or manufacturer's instructions.
Advertisement: Buying Bupropion SR No Prescription
| Dosage |
Quantity |
Price |
Pharmacy |
| 150 mg |
30 tablets |
$98 |
MPLLC (US) |
| 150 mg |
60 tablets |
$134 |
MPLLC (US) |
| 150 mg |
90 tablets |
$168 |
MPLLC (US) |
| 150 mg |
120 tablets |
$198 |
MPLLC (US) |
- US based online pharmacy. All orders are shipped from US.
- Payment methods: Visa, Money Order.
- Customer service: 1-888-738-3822 (9am - 6pm PST), customersupport@mpllc.net
- Delivery: FedEx next day (Overnight) air delivery. You are
guaranteed to receive it.
- No prior prescription required.
- Free online doctor consultation.
- Quality of the medication you are buying: FDA approved Bupropion SR.
Bupropion medical uses:
Bupropion hydrochloride, an antidepressant of the aminoketone class, is
chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake
inhibitor, or other known antidepressant agents. Its structure closely
resembles that of diethylpropion; it is related to phenylethylamines.
Bupropion is indicated for the treatment of major depressive disorder
and smoking cessation.
Contraindications:
- seizure disorder
- current or prior diagnosis of bulimia or anorexia nervosa
- concurrent treatment with or within 14 days of discontinuation of
MAO inhibitors
- concurrent treatment with multiple bupropion products (ie, coadministration
of Zyban for smoking cessation and Wellbutrin for depression)
- abrupt discontinuation of alcohol or sedatives
- hypersensitivity to bupropion or any other component of the product.
Bupropion dosage:
Depression:
Immediate-release: 100 mg two times per day initially; may increase
to 100 mg tree times per day after 3 days (max daily dose, 450 mg; max
single dose, 150 mg).
Sustained-release: 150 mg once daily initially; may increase to
150 mg two times per day as early as day 4 of therapy (max daily dose,
400 mg; max single dose, 200 mg).
Extended-release: 150 mg once daily initially; may increase to
300 mg once daily as early as day 4 of therapy (max daily dose, 450 mg).
Dosing conversion between immediate, sustained, and extended release
products: Convert using same total daily dose (up to the maximum recommended
dose for a given dosage form), but adjust frequency as indicated for sustained
(twice daily) or extended (once daily) release products.
Foods: May be taken without regard to meals.
Side effects:
- Cardiovascular: tachycardia (11%); palpitation (6%); cardiac
arrhythmia (5%); flushing, hypertension (4%); hot flashes, hypotension
(3%); syncope (1%); edema (at least 1%); orthostatic hypotension, third
degree heart block (postmarketing).
- Dermatologic: sweating (22%); rash (8%); pruritus (4%); urticaria
(2%); nonspecific rashes (at least 1%); angioedema, exfoliative dermatitis,
Stevens-Johnson syndrome (postmarketing).
- Central nervous system: agitation (32%); insomnia (31%); headache
(26%); dizziness (22%); tremor (21%); sedation (20%); disturbed concentration
(9%); akinesia/bradykinesia, anxiety, confusion (8%); hostility (6%);
fatigue, nervousness (5%); impaired sleep quality, migraine, sensory
disturbances (4%); decreased libido, decreased memory, irritability,
somnolence (3%); CNS stimulation, paresthesia (2%); delusions (1%);
ataxia/incoordination, decreased sexual function, depression, dyskinesia,
dystonia, hallucinations, increased libido, mania/hypomania, myoclonus,
seizure (at least 1%); abnormal dreams, coma, delirium, paresthesia,
restlessness, unmasking tardive dyskinesia (postmarketing).
- Gastrointestinal: dry mouth (28%); constipation (26%); nausea/vomiting
(23%), weight loss (23%), anorexia (18%), weight gain (14%), abdominal
pain (9%); diarrhea (7%); increased appetite, taste perversion, vomiting
(4%); dyspepsia, gustatory disturbance (3%); dysphagia (2%); stomatitis
(at least 1%); esophagitis (postmarketing).
- Genitourinary: urinary frequency, menstrual complaints (5%);
impotence (3%); urinary retention, urinary urgency, vaginal hemorrhage
(2%); UTI (1%); nocturia (at least 1%).
- Musculoskeletal: myalgia (6%); arthralgia (4%); arthritis (3%);
akathisia, muscle spasm, twitch (2%); arthralgia, muscle rigidity, muscle
weakness, myalgia, rhabdomyolysis (postmarketing) .
- Special senses: blurred vision (15%), tinnitus (5%), auditory
disturbance (5%).
- Respiratory: upper respiratory infection (9%), pharyngitis
(3%), cough increased (1-4%), sinusitis (1-5%).
- Hematologic-Lymphatic: altered PT or INR, ecchymosis, leukocytosis,
leukopenia, thrombocytopenia (postmarketing).
Precautions:
- Children. Bupropion is not FDA approved for use in children.
- Elderly. Use with caution. Because elderly patients are more
likely to have decreased renal function, use care in dose selection
and consider monitoring renal function.
- Bipolar depression. May worsen psychosis in some patients or
precipitate a shift to mania or hypomania in patients with bipolar disorder.
- Renal & Hepatic Function. Use with caution; reduce frequency
and/or dose as needed.\
- Cardiovascular effects. Use caution in patients with cardiovascular
disease, history of hypertension, or coronary artery disease; treatment-emergent
hypertension (including some severe cases) has been reported.
- Seizures. The risk of seizures is dose-dependent and increased
in patients with a history of seizures, anorexia/bulimia, head trauma,
CNS tumor, severe hepatic cirrhosis, abrupt discontinuation of sedative-hypnotics
or ethanol, medications which lower seizure threshold (antipsychotics,
antidepressants, theophyllines, systemic steroids), stimulants, or hypoglycemic
agents.
Drug interactions:
- Alcohol: Adverse neuropsychiatric events or reduced alcohol
tolerance may occur. The consumption of alcohol during treatment with
bupropion should be minimized or avoided.
- Amantadine, levodopa: Incidence of bupropion side effects may
be increased.
- Drugs that lower seizure threshold (antipsychotics, other antidepressants,
theophylline, systemic steroids, etc.): Concurrent administration
these agents with bupropion and agents should be undertaken only with
extreme caution. Low initial dosing and small gradual dose increases
should be employed.
- Anticonvulsants (carbamazepine, phenobarbital, phenytoin):
May decrease bupropion serum concentrations.
- CYP2B6 inhibitors (clopidogrel, cyclophosphamide, orphenadrine,
thiotepa, ticlopidine): May increase bupropion plasma levels and
risk of adverse effects.
- MAO inhibitors, selegiline: Risk of acute bupropion toxicity.
- Metoprolol: Risk of bradycardia.
- Nicotine Transdermal System: Risk of hypertension.
- Warfarin: Risk of hemorrhagic or thrombotic complications.
Pregnancy & Lactation
Pregnancy category C
A slight increase in malformations was observed in some animal studies.
In studies conducted in rats and rabbits, bupropion was administered orally
at doses up to 450 and 150 mg/kg/day, respectively (approximately 11 and
7 times the maximum recommended human dose), during the period of organogenesis.
No clear evidence of teratogenic activity was found in either species;
however, in rabbits, slightly increased incidences of fetal malformations
and skeletal variations were observed at the lowest dose tested (25 mg/kg/day,
approximately equal to the MRHD) and greater. Decreased fetal weights
were seen at 50 mg/kg and greater.
One study has been conducted in pregnant women. This retrospective, managed-care
database study assessed the risk of congenital malformations overall,
and cardiovascular malformations specifically, following exposure to bupropion
in the first trimester compared to the risk of these malformations following
exposure to other antidepressants in the first trimester and bupropion
outside of the first trimester. This study included 7,005 infants with
antidepressant exposure during pregnancy, 1,213 of whom were exposed to
bupropion in the first trimester. The study showed no greater risk for
congenital malformations overall, or cardiovascular malformations specifically,
following first trimester bupropion exposure compared to exposure to all
other antidepressants in the first trimester, or bupropion outside of
the first trimester. The results of this study have not been corroborated.
Bupropion should be used during pregnancy only if the potential benefit
justifies the potential risk to the fetus.
Nursing mothers
Bupropion and its metabolites are secreted in human milk. Because of the
potential for serious adverse reactions in nursing infants from bupropion,
a decision should be made whether to discontinue nursing or to discontinue
the drug, taking into account the importance of the drug to the mother.
Overdose:
Contact your doctor or pharmacist immediately. Symptoms of overdose may
include cardiac arrest, ECG changes or arrhythmias, hallucinations, loss
of consciousness, seizures, sinus tachycardia.
Missed dose:
If a dose is missed, take it as soon as possible. If several hours have
passed or if it is nearing time for the next dose, do not double the dose
to catch up, unless advised by your doctor. If more than one dose is missed,
contact your doctor or pharmacist.
Storage:
Store it at room temperature and away from excess heat and moisture (not
in the bathroom).
Price:
If you would like to buy Bupropion SR with no prescription online, choose
the offer from the above table.
References:
- 1. U.S. Food and Drug Administration. Wellbutrin (Bupropion) U.S.
Prescribing Information. Available at (PDF format): Prescribing
Information
- 2. U.S. Food and Drug Administration. Wellbutrin SR (Bupropion) U.S.
Prescribing Information. Available at (PDF format): Prescribing
Information
- 3. U.S. Food and Drug Administration. Wellbutrin XL (Bupropion) U.S.
Prescribing Information. Available at (PDF format): Prescribing
Information
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