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Fioricet (Butalbital APAP) Prescription
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Basic information
- Generic name: Butalbital/Acetaminophen/Caffeine
- Brand/Trade names: Alagesic, Geone, Fioricet, Margesic, Repan
- Dosages: 50/325/40 mg tablets
- Pharmacologic category: Combined Analgesic
- Habit forming? Yes
- Pregnancy risk factor: C
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Medical uses
Fioricet, introduced in the US in the 1960s, is a pain reliever and sedative used to relieve tension headaches, and sometimes other types of pain. According to the customer reviews, Fioricet (Butalbital APAP Caffeine) is a very popular prescription for migraine. However, butalbital-containing compounds are prescribed for migraines without FDA approval.
More details about ordering Fioricet without prior prescription.
Fioricet consists of
a fixed combination of butalbital 50 mg, acetaminophen 325 mg
and caffeine 40 mg. Acetaminophen is a pain reliever and fever
reducer (antipyretic). Butalbital is in a class of drugs called barbiturates
that slow down central nervous system causing relaxation. Caffeine
is believed to constrict dilated blood vessels that may contribute
to tension headaches. |
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Pharmacological characteristics
- Elimination half-life:
Butalbital: 35 hours
Acetaminophen: 1.25-3 hours, may be increased by liver damage
and following overdosage
Caffeine: 3 hours
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Benefits
- proven efficacy in the treatment of tension headache (2)
- may be effective as reserve medication or when other medicines
are ineffective or cannot be used (2)
- superior to acetaminophen with codeine in alleviating emotional
or psychic tension (3)
- Fioricet was also significantly better than acetaminophen
with codeine in relieving this symptom. Certain analyses suggested
the possibility that Fioricet had a faster and more sustained
analgesic effect than acetaminophen with codeine.
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Concerns
- barbiturates may be habit-forming habit-forming and potentially
abusable
- not for extended use
- risk drug-induced headache
- risk of toxicity
- withdrawal syndrome (1)
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Unlabeled uses
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Mode of action
Butalbital has generalized depressant effect on CNS and, in very
high doses, has peripheral effects. Acetaminophen has analgesic
and antipyretic effects; its analgesic effects may be mediated
through inhibition of prostaglandin synthetase enzyme complex.
Caffeine is thought to produce constriction of cerebral blood
vessels. |
Fioricet Reviews and Discussions
| Dosage |
Quantity |
Price |
Pharmacy |
Order |
| 50/325/40 |
30 tablets |
$79 |
MPLLC |
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| 50/325/40 |
30 tablets |
$83 |
JRB |
|
| 50/325/40 |
60 tablets |
$86 |
MPLLC |
|
| 50/325/40 |
60 tablets |
$91 |
JRB |
|
| 50/325/40 |
90 tablets |
$91 |
MPLLC |
|
| 50/325/40 |
90 tablets |
$97 |
JRB |
|
| 50/325/40 |
100 tablets |
$103 |
JRB |
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- Payment options: Visa, Mastercard, Money Order.
- Delivery: FedEx, UPS next day (Overnight)
How to get Fioricet (Butalbital APAP) online prescription?
Before you buy Fioricet or Butalbital APAP you probably should read what other people who have already used this medication say about it. If you believe you need it, you can order online prescription without having to go to the doctor.
All prescriptions are filled at US licensed pharmacy with FDA-approved medications. You will receive Fioricet delivered to your door without delay with next day shipping. |
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References
- 1. Romero CE, Baron JD, Knox AP, Hinchey JA, Ropper AH. Barbiturate
withdrawal following Internet purchase of Fioricet. Arch Neurol.
2004 Jul;61(7):1111-2.
- 2. Solomon S. Butalbital-containing agents: should they be
banned? No. Curr Pain Headache Rep. 2002 Apr;6(2):147-50. PubMed
- 3. Friedman AP, DiSerio FJ. Symptomatic treatment of chronically
recurring tension headache: a placebo-controlled, multicenter
investigation of Fioricet and acetaminophen with codeine. Clin
Ther. 1987;10(1):69-81. PubMed
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Interesting facts
- In 2003 Watson Pharmaceuticals, a maker of generic and brand-name
drugs, acquired the U.S. marketing rights to the Fioricet (butalbital,
apap, caffeine tablets) and Fiorinal (butalbital, aspirin, caffeine capsules)
product lines, for $178 million from Novartis.
- The divested products achieved combined sales of approximately USD
60 million in 2002.
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