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Fioricet

Fioricet (Butalbital APAP) Prescription


Basic information
  • Generic name: Butalbital/Acetaminophen/Caffeine
  • Brand/Trade names: Alagesic, Geone, Fioricet, Margesic, Repan
  • Dosages: 50/325/40 mg tablets
  • Pharmacologic category: Combined Analgesic
  • Habit forming? Yes
  • Pregnancy risk factor: C
Medical uses

Fioricet, introduced in the US in the 1960s, is a pain reliever and sedative used to relieve tension headaches, and sometimes other types of pain. According to the customer reviews, Fioricet (Butalbital APAP Caffeine) is a very popular prescription for migraine. However, butalbital-containing compounds are prescribed for migraines without FDA approval.

More details about ordering Fioricet without prior prescription.

Fioricet consists of a fixed combination of butalbital 50 mg, acetaminophen 325 mg and caffeine 40 mg. Acetaminophen is a pain reliever and fever reducer (antipyretic). Butalbital is in a class of drugs called barbiturates that slow down central nervous system causing relaxation. Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches.

Pharmacological characteristics
  • Elimination half-life:
    Butalbital: 35 hours
    Acetaminophen: 1.25-3 hours, may be increased by liver damage and following overdosage
    Caffeine: 3 hours
Benefits
  • proven efficacy in the treatment of tension headache (2)
  • may be effective as reserve medication or when other medicines are ineffective or cannot be used (2)
  • superior to acetaminophen with codeine in alleviating emotional or psychic tension (3)
  • Fioricet was also significantly better than acetaminophen with codeine in relieving this symptom. Certain analyses suggested the possibility that Fioricet had a faster and more sustained analgesic effect than acetaminophen with codeine.
Concerns
  • barbiturates may be habit-forming habit-forming and potentially abusable
  • not for extended use
  • risk drug-induced headache
  • risk of toxicity
  • withdrawal syndrome (1)
Unlabeled uses
  • migraine headache
Mode of action

Butalbital has generalized depressant effect on CNS and, in very high doses, has peripheral effects. Acetaminophen has analgesic and antipyretic effects; its analgesic effects may be mediated through inhibition of prostaglandin synthetase enzyme complex. Caffeine is thought to produce constriction of cerebral blood vessels.

Fioricet Reviews and Discussions

Dosage Quantity Price Pharmacy Order
50/325/40 30 tablets $79 MPLLC
50/325/40 30 tablets $83 JRB
50/325/40 60 tablets $86 MPLLC
50/325/40 60 tablets $91 JRB
50/325/40 90 tablets $91 MPLLC
50/325/40 90 tablets $97 JRB
50/325/40 100 tablets $103 JRB
  • Payment options: Visa, Mastercard, Money Order.
  • Delivery: FedEx, UPS next day (Overnight)

How to get Fioricet (Butalbital APAP) online prescription?

Before you buy Fioricet or Butalbital APAP you probably should read what other people who have already used this medication say about it. If you believe you need it, you can order online prescription without having to go to the doctor.

All prescriptions are filled at US licensed pharmacy with FDA-approved medications. You will receive Fioricet delivered to your door without delay with next day shipping.

References
  • 1. Romero CE, Baron JD, Knox AP, Hinchey JA, Ropper AH. Barbiturate withdrawal following Internet purchase of Fioricet. Arch Neurol. 2004 Jul;61(7):1111-2.
  • 2. Solomon S. Butalbital-containing agents: should they be banned? No. Curr Pain Headache Rep. 2002 Apr;6(2):147-50. PubMed
  • 3. Friedman AP, DiSerio FJ. Symptomatic treatment of chronically recurring tension headache: a placebo-controlled, multicenter investigation of Fioricet and acetaminophen with codeine. Clin Ther. 1987;10(1):69-81. PubMed
Interesting facts

fioricet

watson
  • In 2003 Watson Pharmaceuticals, a maker of generic and brand-name drugs, acquired the U.S. marketing rights to the Fioricet (butalbital, apap, caffeine tablets) and Fiorinal (butalbital, aspirin, caffeine capsules) product lines, for $178 million from Novartis.
  • The divested products achieved combined sales of approximately USD 60 million in 2002.


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